#Methotrexate #Aspect #Results #Mechanism #Motion #Indications [ad_1] Methotrexate stays a cornerstone within the remedy of rheumatoid arthritis and different rheumatic ailments. Folate antagonism is understood to contribute to the antiproliferative results which are vital within the motion of methotrexate towards malignant ailments, however concomitant administration of folic or folinic acid doesn’t diminish the anti-inflammatory potential