#PPIs #Mnemonic #USMLE
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Proton pump inhibitors or PPIs for brief are medication that inhibit proton or acid manufacturing by your abdomen. They do that particularly by blocking an ATPase pump that pumps acidic protons out of cells in alternate for bringing potassium into the cell. Discount of abdomen acid is beneficial in treating acid-mediated problems like peptic ulcers or acid reflux disease. Uncomfortable side effects of utilizing PPIs embody elevated fracture danger on account of decreased GI calcium absorption, and elevated susceptibility to infections. Lastly, PPIs inhibit CYP or cytochrome P450 enzymes, resulting in a major drug interplay danger.
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#USMLE #Step1 #Pharm #PPIs #protonpumpinhibitors
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