Tag: PLAB

#Polycystic #OvaryPCOD #illness #details #Watch #Excessive #yields #usmle #neet #plab #fmge
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Polycystic Ovary(PCOD)illness|Can Polycystic Ovarian illness be cured?

Polycystic ovary syndrome (PCOS)|

Is PCOS is a critical illness?

What’s the fundamental reason for PCOS?

At what age PCOS begins?

Can PCOS sufferers get common durations?

This video reveals salient options of Polycystic Ovarian illness together with etiopathogenesis, scientific options, analysis, remedy features, and a excessive yield case dialogue.

Additionally watch:

https://www.youtube.com/playlist?listing=PL0-Q_iDcO3ae0lhDquJqvb7Mgl_xRsy3-

#Polycystic Ovary Illness
#PCOD
#PCOS
#Stein Leventhal Syndrome
#usmle
#usmle step 1
#plab
#fmge
#neet pg

A.ok.a. PCOS/PCOD or Stein-Leventhal syndrome
-As much as 6% of reproductive age girls
-Most typical reason for anovulatory infertility
-Def: Quite a few cystic follicles or follicle cysts
The initiating occasion in PCOD shouldn’t be clear
Poor regulation of number of enzymes concerned in androgen biosynthesis
Excessive amplitude GnRH pulses result in elevated pituitary launch of LH.
LH stimulates theca cells to provide androgens
Androgens transformed within the fats tissue into estrogens (estrone)
Estrone blocks FSH manufacturing
With out FSH oocyte doesn’t produce estradiol
Degeneration of follicle and formation of cyst
Most vital – a rise of LH and reduce of FSH (LH/FSH greater than 2)
Insulin resistance additionally performs a job: Insulin stimulates theca cell secretion of androgens
Scientific Options:
Oligomenorrhoea
Dysmenorrhoea
Anovulation
Weight problems
Hirsuitism
Elevated threat of endometrial hyperplasia/Carcinoma

Lab Prognosis:
Elevated Androgen
Elevated LH
Regular or Low FSH
Elevated AMH
Elevated or regular Estrogen

Morphology:

Enlarged ovaries with a easy, gray-white outer cortex studded with subcortical cysts 0.5 to 1.5 cm in diameter
-Thickened, fibrotic superficial cortex beneath that are innumerable follicle cysts
– Hyperplasia of the theca interna (follicular hyperthecosis)
-No corpora lutea

Therapy:
Clomiphene Citrate
FSH
Weight reduction

Stromal hyperthecosis:

A.ok.a. stromal hyperplasia
-Mostly seen in postmenopausal girls

Morphology:
1. Bilateral uniform enlargement of the ovaries (as much as 7 cm), no cysts!
2. White to tan (yellow, brownish) look on sectioning
Micro:
1. Hypercellular stroma
2.luteinization of the stromal cells

#polycysticovarysyndrome
#polycysticovariandisease
#usmle
#plab
#fmge
#neetpg
#pathology
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