Tag: Blood Brain Barrier

  • Dr. John Boockvar Of Lenox Hill Hospital Talks New Surgical Approach To Deal with Glioblastoma

    Dr. John Boockvar Of Lenox Hill Hospital Talks New Surgical Approach To Deal with Glioblastoma

    #John #Boockvar #Lenox #Hill #Hospital #Talks #Surgical #Approach #Deal with #Glioblastoma
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    We sit down for an interview with Dr. John Boockvar, vice chair of neurosurgery at Lenox Hill Hospital, who began a first-in-human scientific analysis research involving a brand new surgical approach to deal with glioblastoma multiforme (GBM) – essentially the most aggressive type of mind most cancers.

    Dr. Boockvar was one of many neurosurgeons featured on the extremely praised Netflix sequence, Lenox Hill. See hyperlink right here:

    https://www.netflix.com/title/80201728

    Concerning the Process:
    After normal tumor resection, the affected person’s personal scalp tissue is harvested, rotated and engrafted and used to line the resected tumor cavity. It’s our hope that by doing tissue autograft, it should permit to bypass the blood mind barrier so chemotherapeutics and immune cells can higher attain the tumor web site, enhancing remedy for GBM sufferers.

    The research entitled, “Tissue Autograft to Bypass the Blood Mind Barrier (BBB) in Human Glioblastoma Multiforme,” is being led by John Boockvar, MD, the hospital’s vice chair, neurosurgery and director of Lenox Hill’s Mind Tumor Middle. To be eligible for the research, contributors should be 18 years of age or older and plan to bear resection of identified or suspected GBM.

    Press launch concerning the first affected person for additional background:

    https://www.northwell.edu/information/lenox-hill-first-to-study-using-tissue-autograft-for-gbm-tumors-in-humans

    Lenox Hill’s neurosurgery division webpage:
    https://lenoxhill.northwell.edu/neurosurgery

    Social Media:
    Instagram: lhh_neurosurgery
    Twitter: @LenoxNeurosurg

    Dr. Boockvar, background hyperlink:

    https://www.northwell.edu/about/management/john-andrew-boockvar-md

    Dr. Boockvar’s analysis on the Feinstein Institutes for Medical Analysis:

    https://feinstein.northwell.edu/institutes-researchers/our-researchers/john-boockvar-md
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  • Dystonia, Chorea, Athetosis, Myoclonus – Motion problems

    Dystonia, Chorea, Athetosis, Myoclonus – Motion problems

    #Dystonia #Chorea #Athetosis #Myoclonus #Motion #problems
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    Dystonia is a dynamic dysfunction that modifications in severity based mostly on the exercise and posture. Dystonia could assume a sample of overextension or over-flexion of the hand, inversion of the foot, lateral flexion or retroflection of the top, torsion of the backbone with arching and twisting of the again, forceful closure of the eyes, or a set grimace. It might come to an finish when the physique is in motion and through sleep. (See quotation under)

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    Subject References
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    🌎https://www.aans.org/en/Sufferers/Neurosurgical-Circumstances-and-Remedies/Dystonia
    🌎https://www.ninds.nih.gov/Problems/All-Problems/Chorea-Data-Web page
    🌎https://www.healthline.com/well being/athetosis

    Description’s Quotation
    —————————————————
    Pana A, Saggu BM. Dystonia. [Updated 2020 Sep 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan

    Music Credit score
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    Title: Ticker by Silent Companion
    Title: At all times Dreaming by Inside Attain
    Title: Drift by Drift

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    Microphone: Blue Yeti X Skilled Condenser
    Audio Software program: Adobe Audition CC 2020
    Video Software program: Filmora-X and Adobe After Results CS 6
    Thumbnail Software program: Adobe Photoshop CS 6

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  • Serotonin Syndrome – Medicines That Causes It

    Serotonin Syndrome – Medicines That Causes It

    #Serotonin #Syndrome #Medicines
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    Serotonin syndrome is a probably life-threatening syndrome that’s precipitated by means of serotonergic medicine and overactivation of each the peripheral and central postsynaptic 5HT-1A and, most notably, 5HT-2A receptors. This syndrome consists of a mixture of psychological standing modifications, neuromuscular hyperactivity, and autonomic hyperactivity.
    Serotonin syndrome can happen by way of the therapeutic use of serotonergic medicine alone, an intentional overdose of serotonergic medicine, or classically, on account of a posh drug interplay between two serotonergic medicine that work by completely different mechanisms. A large number of drug combos may end up in serotonin syndrome. (See quotation beneath)

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    🥼 Bodily Examination App
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    Matter References
    —————————————————
    🌎https://www.uptodate.com/contents/serotonin-syndrome-serotonin-toxicity
    🌎https://www.nps.org.au/australian-prescriber/articles/serotonin-syndrome
    🌎https://www.healthnavigator.org.nz/health-a-z/s/serotonin-syndrome/
    🌎https://medlineplus.gov/ency/article/007272.htm

    Description’s Quotation
    —————————————————
    Volpi-Abadie J, Kaye AM, Kaye AD. Serotonin syndrome. Ochsner J. 2013;13(4):533-540

    Music Credit score
    —————————————————
    Title: Ticker by Silent Accomplice
    Title: All the time Dreaming by Inside Attain
    Title: Drift by Drift

    Software program and {Hardware}
    —————————————————
    Microphone: Blue Yeti X Skilled Condenser
    Audio Software program: Adobe Audition CC 2020
    Video Software program: Filmora-X and Adobe After Results CS 6
    Thumbnail Software program: Adobe Photoshop CS 6

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