Platelets

Platelets

  1. Derived from megakaryocytes
  2. Functions - adhesion, activation, secretion, aggregation
  3. Release: serotonin, adrenalin, ADP, prostaglandins, thromboxanes

 

Classification of platelet abnormalities

  1. Disorders of number
    • Thrombocytopenia: bleeding - petechiae, ecchymosis, epistaxis
    • Thrombocythaemia: splenomegaly, haemorrhages, thrombotic episodes
  2. Disorders of function
    • Thrombasthenia