Organisation resolution and repair

Organisation

  • Transformation of inanimate material (clot, thrombus, pus) into living tissue responsive to growth control factors of the body
  • Achieved by replacement with granulation tissue

Resolution

  • Replacement of damaged tissue by fully functional tissue normally found at that site (no scar tissue)
  • Found in liver, bone marrow, mucosal defects, minor injury to epidermis

Repair

  • Replacement of damaged tissue by fibrosis or gliosis filling defect but has no intrinsic specialised function relevant to organ
  • Occurs in most instances