Calculi

Calculi

  • Abnormal mass of precipitated solid material in a duct
  1. Prostatic (commonest: most TURP and prostatectomy specimens have calculi)
  2. Biliary
  3. Urinary
  4. Pancreatic
  5. Salivary

Principles of formation

  1. Flow
    • Stasis
  2. Wall
  3. Constituents
    • Nidus (desqumated cells, secretion, infection)
    • Increased colloid / reduced solvent
    • Change in pH

Complications of Calculi

(Depends on site and size)

Obstruction
Haemorrhage
Infection
Stricture
Perforation
Metaplasia/Malignant change