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Professor Shane Crotty, PhD solutions a collection of COVID 19 vaccine questions together with what are the possibilities of long-term unwanted side effects? How secure is RNA vaccine (i.e. Pfizer / BioNTech and Moderna Vaccines) expertise? How lengthy does mRNA from a vaccine keep in our cells? What else goes in vaccines? How lengthy does immunity final? Why are T-Cells so vital? Why does Pfizer’s vaccine want to remain SO chilly?
Shane Crotty, PhD is a Professor on the La Jolla Institute for Immunology, Heart for Infectious Illness and Vaccine Analysis, Crotty Lab. Professor Crotty additionally has a tutorial appointment with the College of California San Diago. See his full bio right here: https://www.lji.org/labs/crotty/#overview
Professor Crotty on Twitter: https://twitter.com/profshanecrotty
Interviewer: Kyle Allred, Doctor Assistant, Producer and Co-Founding father of MedCram.com
See our new interview with Prof. Crotty on how virus mutations (UK variant and S. African variant) could also be impacting COVID-19 transmission and vaccine efficacy.
Analysis referenced on this video from Prof. Crotty and his workforce was revealed Jan. 6, 2021, within the prestigious Journal Science: https://science.sciencemag.org/content material/early/2021/01/05/science.abf4063.full
New York Occasions article highlighting Prof. Shane Crotty’s analysis: https://www.nytimes.com/2020/11/17/well being/coronavirus-immunity.html
00:00 Introducing Prof. Shane Crotty’s Analysis
0:35 How lengthy does COVID-19 “immune reminiscence” final?
0:57 The three major points of immune reminiscence: antibodies, killer T cells, and helper T cells
2:25 The anatomy (protein make-up) of SARS-CoV-2
3:02 Why is spike protein the first goal?
5:17 Might a mutation permit SARS-CoV-2 to contaminate with out spike protein?
7:02 Using lipid nanoparticles to ship mRNA and the function of RNA usually
9:52 What human cells does an RNA vaccine go into?
10:36 How lengthy does mRNA from a vaccine keep in human cells?
11:44 What else goes in vaccines in addition to mRNA and lipid nanoparticles? Any preservatives or adjuvants?
12:30 Why are adjuvants utilized in many vaccines?
14:08 Protein manufacturing from mRNA
15:00 Why make the most of the “further” step of mRNA to code for protein antigens?
17:28 Are mRNA vaccines the way forward for vaccine improvement?
19:18 Any likelihood for mRNA to enter our cells’ nucleus?
20:55 The immune response to a coronavirus vaccine
23:17 Anticipated signs from immune response to a vaccine vs. vaccine unwanted side effects
25:50 Ought to individuals who’ve had COVID-19 get vaccinated?
27:27 Immunity from COVID vaccine vs. a pure an infection
28:30 Why does the Pfizer vaccine must be saved so chilly?
29:04 What would you say to a member of the family who’s nervous a couple of rushed vaccine and RNA expertise?
32:37 What about the potential of long run unwanted side effects from RNA vaccines?
33:30 What’s subsequent for Shane Crotty’s analysis workforce?
(This video was recorded on December 16, 2020).
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PREVIOUS / RECENT MEDCRAM COVID-19 INTERVIEWS:
Vitamin D and COVID 19: The Proof for Prevention and Remedy of Coronavirus (SARS CoV 2) with Professor Roger Seheult, MD https://youtu.be/ha2mLz-Xdpg
At House COVID 19 Antigen Testing and Vaccine Replace with Professor Michael Mina, MD https://youtu.be/CjphzlV5DYo
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